First lady Peng leads fight against tuberculosis

Source: ChinaDaily

24/3/2016

Researchers snip HIV from infected cells, suggesting a cure for Aids is possible

Source: South China Morning Post

University researchers have used a gene-editing technique to remove HIV DNA from the type of human immune cells where the virus maintains a reservoir of infection.

The experiment, building on the Philadelphia Temple University researchers’ previous HIV gene-editing work, was conducted in T cells growing in lab dishes. Whether it works in actual patients remains to be seen.

Still, the study bolsters the concept that HIV, the virus that causes Aids, can be cured, not just controlled in a latent stage by antiviral drugs.

Achieving a cure has been a bedevilling challenge because there has been no way to eliminate latent viral DNA from an infected cell’s genetic code without destroying that cell.

“We might be able someday to cure HIV right here in Philadelphia,” said Temple neurobiologist Kamel Khalili, leader of the study published online this month in the journal Scientific Reports.

A more reserved view was offered by Manjunath Swamy, an infectious disease specialist who has used gene-editing in HIV research at Texas Tech University Health Sciences Centre in El Paso.

Swamy pointed out that when patients take anti-HIV drugs, viral replication is so suppressed that only about one immune T cell in a million has a latent infection. Gene-editing “these rare cells is a major hurdle, precluding its clinical use anytime soon,” he said.

The gene-editing technology, called CRISPR, is barely five years old and has not yet been used in patients. Even so, it is seen as a potentially revolutionary medical tool. It combines a synthetic “guide RNA” — a genetic version of the search function in a word processor — with an enzyme that acts like molecular scissors.

For a study published in 2014, the Temple researchers used CRISPR to eradicate latent HIV primarily from certain immune cells that harbour the virus in the brain. They also showed that the guide RNA and scissor enzyme persisted in the cleared cells, thus preventing reinjection by HIV. More

22/3/2016

HIV Treatment Drugs in China Markets

Source: med gadget

China’s demand for HIV Treatment Drugs has grown at a fast pace in the past decade. In the next decade, both production and demand will continue to grow. The Chinese economy maintains a high speed growth which has been stimulated by the consecutive increases of industrial output, import & export, consumer consumption and capital investment for over two decades. This new study examines China’s economic trends, investment environment, industry development, supply and demand, industry capacity, industry structure, marketing channels and major industry participants. Historical data (2005, 2010 and 2015) and long-term forecasts through 2020 and 2025 are presented. Major producers in China are profiled.

The primary and secondary research is done in China in order to access up-to-date government regulations, market information and industry data. Data were collected from the Chinese government publications, Chinese language newspapers and magazines, industry associations, local governments’ industry bureaus, industry publications, and our in-house databases. Interviews are conducted with Chinese industry experts, university professors, and producers in China. Economic models and quantitative methods are applied in this report to project market demand and industry trends. Metric system is used and values are presented in either Yuan (RMB, current price) and/or US dollars.

Our market research reports provide hard-to-find market data and analyses. Today, China has the largest market in the world. Tremendous fast-growing markets for imports and business opportunities for companies around the world. If you want to expand your business or sell your products in China, our research reports provide the insights and projections into Chinese markets necessary for you to do so.